Interactor 1: TRPC1 (P48995)
Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1)
Gene: TRPC1

Interactor 2: PKD2 (Q13563)
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)
Gene: PKD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 10097141, 25114176
Identification Methods pull down, two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~PKD_channel
Common GO terms GO:0005102 - signaling receptor binding
GO:0005261 - monoatomic cation channel activity
GO:0005886 - plasma membrane
GO:0006816 - calcium ion transport
GO:0034703 - cation channel complex
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 793
Hs

1 968
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024