Interactor 1: TRPC1 (P48995)
Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1)
Gene: TRPC1

Interactor 2: ITPR3 (Q14573)
Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)
Gene: ITPR3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 10980191, 11290752, 19052258
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans
Common GO terms GO:0005886 - plasma membrane
GO:0043235 - receptor complex
GO:0051592 - response to calcium ion
GO:0070679 - inositol 1,4,5 trisphosphate binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 793
Hs

1 2671
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Last updated: 15 Jul 2024