HitPredict

Interactor 1: MRP (P49006)
MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS)
Gene: MARCKSL1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007015 - actin filament organization GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 195 Hs			1 191
+	Hs
		564451 MRP_HUMAN (1-195): 5.47e-77: 230: 100.00		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		823246 MRP_HUMAN (1-195): 5.47e-77: 230: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		823248 MRP_HUMAN (1-195): 5.47e-77: 230: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		823241 MRP_HUMAN (1-195): 5.47e-77: 230: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545259 MRP_HUMAN (1-195): 5.47e-77: 230: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		823265 MRP_HUMAN (1-195): 5.47e-77: 230: 100.00		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82