Interactor 1: PAXI (P49023)
Paxillin
Gene: PXN

Interactor 2: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 10625692, 27880917, 28514442, 28675297, 9497381, 33961781, 10400685, 34079125, 35271311, 19167335
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, phosphatase assay
Interaction Type direct interaction, physical association, association, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005925 - focal adhesion
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 591
Hs

1 780
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024