Interactor 1: PAXI (P49023)
Paxillin
Gene: PXN
Interactor 2: FAK1 (Q05397)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.990 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30120307, 22761432, 28415719, 11514617, 31980649, 10330411, 9054445, 15987550, 8922390, 34079125, 9756887, 10455189, 25391654, 9422762, 11919182, 9442086, 10753828, 32707033, 10980697, 11113628 and 5 others
more... |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, far western blotting |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Focal_AT~Paxillin |
| Common GO terms | GO:0001725 - stress fiber GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0005938 - cell cortex and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
