HitPredict

Interactor 1: PAXI (P49023)
Paxillin
Gene: PXN

Interactor 2: LIMD1 (Q9UGP4)
LIM domain-containing protein 1
Gene: LIMD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0016477 - cell migration GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 591 Hs			1 676
+	Hs
		238998 LPXN_HUMAN (186-590): 2.88e-109: 334: 50.37		LIMD1_HUMAN (1-676): 1.67e-124: 386: 100.00
+	Hs
		823405 PAXI_HUMAN (12-591): 3.81e-117: 361: 100.00		ZYX_HUMAN (107-663): 6.52e-65: 226: 23.63
+	Hs
		238967 LPXN_HUMAN (186-590): 2.88e-109: 334: 50.37		ZYX_HUMAN (107-663): 6.52e-65: 226: 23.63
+	Hs
		816231 PAXI_HUMAN (12-591): 3.81e-117: 361: 100.00		LIMS1_HUMAN (455-661): 5.2e-39: 148: 18.84
+	Hs
		238953 LPXN_HUMAN (186-590): 2.88e-109: 334: 50.37		LIMS1_HUMAN (455-661): 5.2e-39: 148: 18.84
+	Hs
		823353 PAXI_HUMAN (12-591): 3.81e-117: 361: 100.00		PAXI_HUMAN (537-674): 1.04e-25: 114: 25.33
+	Hs
		816283 ZN160_HUMAN (124-529): 3.05e-95: 310: 11.17		LIMS1_HUMAN (455-661): 5.2e-39: 148: 18.84
+	Hs
		823403 PAXI_HUMAN (12-591): 3.81e-117: 361: 100.00		TRIP6_HUMAN (102-601): 1.09e-12: 72.8: 15.29
+	Hs
		200167 PAXI_HUMAN (12-591): 3.81e-117: 361: 100.00		TGFI1_HUMAN (488-633): 1.52e-09: 62.8: 31.29
+	Hs
		200190 TGFI1_HUMAN (1-532): 4.62e-63: 216: 24.91		TES_HUMAN (349-654): 1.52e-56: 199: 20.32
+	Hs
		238982 LPXN_HUMAN (186-590): 2.88e-109: 334: 50.37		LPP_HUMAN (160-669): 1.29e-13: 76.3: 13.69
+	Hs
		238992 LPXN_HUMAN (186-590): 2.88e-109: 334: 50.37		PDLI7_HUMAN (153-524): 4.78e-13: 73.9: 11.41
+	Hs
		238966 LPXN_HUMAN (186-590): 2.88e-109: 334: 50.37		TRIP6_HUMAN (102-601): 1.09e-12: 72.8: 15.29
+	Hs
		549162 ZN250_HUMAN (70-463): 7.31e-70: 237: 13.07		ZN345_HUMAN (236-476): 1.58e-33: 136: 5.81
+	Hs
		1044590 FHL3_HUMAN (382-590): 1.13e-57: 196: 28.64		FHL2_HUMAN (498-663): 5.7e-32: 127: 23.81
+	Ce
		107596 PXL1_CAEEL (143-532): 1.7e-57: 200: 19.75		G5EFG1_CAEEL (533-669): 8.55e-24: 108: 20.86
+	Hs
		1136614 FHL5_HUMAN (381-590): 9.47e-63: 210: 29.44		PDLI7_HUMAN (153-524): 4.78e-13: 73.9: 11.41
+	Hs
		563267 ZN708_HUMAN (124-444): 2.44e-59: 209: 9.54		ZN543_HUMAN (235-405): 4.83e-13: 74.1: 8.19
+	Hs
		1044595 FHL3_HUMAN (382-590): 1.13e-57: 196: 28.64		TRIP6_HUMAN (102-601): 1.09e-12: 72.8: 15.29