Interactor 1: PAXI (P49023)
Paxillin
Gene: PXN

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 17898078, 17467235, 31980649, 34079125, 16628223, 12629171, 25742295, 36963288, unassigned2173
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~LIM
Common GO terms GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0030027 - lamellipodium
GO:0046872 - metal ion binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 591
Hs

1 761
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024