HitPredict

Interactor 1: PAXI (P49024)
Paxillin
Gene: PXN

Interactor 2: CRK (Q04929)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Gallus gallus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.19	0.60	0.338

Property	Details
Experiments	7537852
Identification Methods	experimental interaction detection
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Gg			1 305
+	Hs
		802534 PAXI_HUMAN (12-559): 8.56e-121: 370: 83.48		CRK_HUMAN (1-305): 3.99e-65: 208: 83.93
+	Rn
		1144373 PAXI_RAT (12-559): 2.44e-119: 366: 83.85		CRK_RAT (1-305): 3.82e-65: 208: 83.61
+	Mm
		1144841 PAXI_MOUSE (12-559): 2.14e-115: 356: 82.79		CRK_MOUSE (1-305): 4.54e-65: 208: 83.61
+	Hs
		802806 PAXI_HUMAN (12-559): 8.56e-121: 370: 83.48		CRKL_HUMAN (2-303): 8.48e-58: 189: 52.83
+	Rn
		1137277 PAXI_RAT (12-559): 2.44e-119: 366: 83.85		CRKL_RAT (2-303): 2.28e-57: 188: 52.52
+	Mm
		815096 PAXI_MOUSE (12-559): 2.14e-115: 356: 82.79		CRKL_MOUSE (2-303): 1.98e-57: 188: 52.20
+	Hs
		823423 PAXI_HUMAN (12-559): 8.56e-121: 370: 83.48		DNMBP_HUMAN (103-305): 4.04e-40: 151: 24.40
+	Hs
		209008 PAXI_HUMAN (12-559): 8.56e-121: 370: 83.48		NCK2_HUMAN (134-215): 2.35e-10: 62.7: 21.43
+	Hs
		823365 PAXI_HUMAN (12-559): 8.56e-121: 370: 83.48		GRB2_HUMAN (241-293): 1.05e-10: 62.1: 24.07
+	Hs
		557639 PAXI_HUMAN (12-559): 8.56e-121: 370: 83.48		NCK1_HUMAN (24-213): 5.17e-10: 61.7: 15.54
+	Hs
		802757 ZKSC7_HUMAN (61-322): 4.13e-23: 105: 7.01		CRK_HUMAN (1-305): 3.99e-65: 208: 83.93
+	Hs
		209005 LIMS1_HUMAN (325-558): 2.79e-67: 222: 31.95		NCK2_HUMAN (134-215): 2.35e-10: 62.7: 21.43
+	Hs
		300996 ABLM3_HUMAN (384-558): 2.82e-39: 154: 27.96		GRB2_HUMAN (241-293): 1.05e-10: 62.1: 24.07
+	Mm
		250825 FHL2_MOUSE (297-435): 3.65e-24: 104: 25.87		PLCG2_MOUSE (4-302): 3.78e-26: 110: 15.34
+	Hs
		562668 ZKSC7_HUMAN (61-322): 4.13e-23: 105: 7.01		PLCG2_HUMAN (4-302): 8.06e-26: 109: 15.34
+	Hs
		924889 PDLI7_HUMAN (441-558): 5.72e-33: 133: 33.90		GRB2_HUMAN (241-293): 1.05e-10: 62.1: 24.07
+	Dm
		993218 AJUBA_DROME (437-558): 1.03e-26: 116: 26.36		GRAP_DROME (241-293): 7.07e-10: 59.8: 18.52
+	Hs
		209061 TRIP6_HUMAN (433-558): 3.75e-24: 107: 27.91		NCK2_HUMAN (134-215): 2.35e-10: 62.7: 21.43
+	Hs
		1078829 ZYX_HUMAN (444-558): 1.72e-22: 103: 31.36		ITSN1_HUMAN (121-299): 3.09e-10: 63.3: 10.61
+	Hs
		150515 ABLM1_HUMAN (481-558): 1.38e-09: 62.9: 25.64		VAV_HUMAN (200-294): 8.37e-16: 79.8: 16.67