HitPredict

Interactor 1: IGLL5 (B9A064)
Immunoglobulin lambda-like polypeptide 5 (G lambda-1) (Germline immunoglobulin lambda 1)
Gene: IGLL5

Interactor 2: IGLC3 (P0DOY3)
Immunoglobulin lambda constant 3 (Ig lambda chain C region DOT) (Ig lambda chain C region NEWM) (Ig lambda-3 chain C regions)
Gene: IGLC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0003823 - antigen binding GO:0016064 - immunoglobulin mediated immune response GO:0070062 - extracellular exosome GO:0071735 - IgG immunoglobulin complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 214 Hs			1 106
+	Hs
		82378 IGLL5_HUMAN (1-214): 2.02e-82: 245: 100.00		IGLL1_HUMAN (2-106): 1.25e-41: 137: 83.81
+	Hs
		82385 IGLL5_HUMAN (1-214): 2.02e-82: 245: 100.00		HLAF_HUMAN (2-105): 5.33e-40: 137: 19.23
+	Hs
		82374 IGLL5_HUMAN (1-214): 2.02e-82: 245: 100.00		IGLC6_HUMAN (1-106): 1.52e-42: 136: 94.34
+	Hs
		48911 IGLL5_HUMAN (1-214): 2.02e-82: 245: 100.00		IGLC7_HUMAN (1-106): 2.84e-41: 133: 92.45
+	Mm
		595692 IGLL1_MOUSE (36-214): 1.11e-57: 183: 61.45		IGLL1_MOUSE (1-106): 7.64e-39: 130: 66.98
+	Hs
		182246 TPSN_HUMAN (1-203): 1.48e-48: 166: 21.40		HLAA_HUMAN (2-106): 7.15e-40: 137: 20.00
+	Hs
		182247 TPSN_HUMAN (1-203): 1.48e-48: 166: 21.40		DPB1_HUMAN (2-106): 8.2e-40: 134: 29.52
+	Hs
		182250 TPSN_HUMAN (1-203): 1.48e-48: 166: 21.40		HLAC_HUMAN (2-106): 1.79e-38: 133: 20.95
+	Hs
		382258 HLAA_HUMAN (55-208): 1.04e-46: 159: 16.46		HLAA_HUMAN (2-106): 7.15e-40: 137: 20.00
+	Hs
		382321 HLAA_HUMAN (55-208): 1.04e-46: 159: 16.46		HLAF_HUMAN (2-105): 5.33e-40: 137: 19.23
+	Hs
		382467 Q860B5_HUMAN (58-208): 3.74e-47: 159: 17.42		HLAA_HUMAN (2-106): 7.15e-40: 137: 20.00
+	Hs
		353631 IGLL1_HUMAN (1-214): 3.49e-78: 235: 73.83		IGHG1_HUMAN (7-104): 1.06e-10: 58.4: 25.00
+	Hs
		382277 HLAA_HUMAN (55-208): 1.04e-46: 159: 16.46		HLAC_HUMAN (2-106): 1.79e-38: 133: 20.95
+	Hs
		382299 HLAA_HUMAN (55-208): 1.04e-46: 159: 16.46		HLAG_HUMAN (2-106): 1.02e-38: 133: 19.05
+	Hs
		182244 TPSN_HUMAN (1-203): 1.48e-48: 166: 21.40		DQB1_HUMAN (2-100): 1.69e-36: 125: 28.28
+	Hs
		382387 HLAA_HUMAN (55-208): 1.04e-46: 159: 16.46		DRB3_HUMAN (2-100): 8.19e-38: 129: 33.33
+	Hs
		355008 HLAA_HUMAN (55-208): 1.04e-46: 159: 16.46		DQB1_HUMAN (2-100): 1.69e-36: 125: 28.28
+	Hs
		382442 HLAA_HUMAN (55-208): 1.04e-46: 159: 16.46		DRB5_HUMAN (2-100): 2.12e-36: 125: 33.33
+	Hs
		353698 Q8N355_HUMAN (40-214): 5.48e-50: 164: 65.73		IGHG1_HUMAN (7-104): 1.06e-10: 58.4: 25.00