HitPredict

Interactor 1: NR2C2 (P49116)
Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)
Gene: NR2C2

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17626013, 20064081
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 596 Hs			1 693
+	Mm
		824603 NR2C2_MOUSE (1-596): 1.75e-180: 524: 98.32		TAB2_MOUSE (1-693): 7.87e-108: 344: 94.66
+	Hs
		823914 NR2C2_HUMAN (1-596): 0: 527: 100.00		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		824479 NR2C2_HUMAN (1-596): 0: 527: 100.00		CHD7_HUMAN (18-590): 1.32e-19: 96.3: 11.81
+	Hs
		823722 NR2C2_HUMAN (1-596): 0: 527: 100.00		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		823723 NR2C2_HUMAN (1-596): 0: 527: 100.00		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		525297 NR2C1_HUMAN (21-596): 1.19e-132: 402: 60.50		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Dm
		631287 ECR_DROME (68-590): 6.64e-78: 266: 21.67		BRM_DROME (165-665): 1e-43: 172: 12.74
+	Hs
		1030592 STF1_HUMAN (110-583): 1.35e-87: 281: 21.47		Q59FZ6_HUMAN (201-665): 9.94e-39: 156: 11.11
+	Hs
		509925 VDR_HUMAN (95-583): 4.46e-80: 260: 18.86		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		782677 HNF4A_HUMAN (88-274): 1.46e-51: 186: 33.85		CHD7_HUMAN (18-590): 1.32e-19: 96.3: 11.81
+	Hs
		587141 RXRA_HUMAN (1-291): 9.13e-62: 213: 26.82		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		782503 HNF4A_HUMAN (88-274): 1.46e-51: 186: 33.85		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		782595 HNF4A_HUMAN (88-274): 1.46e-51: 186: 33.85		KMT2C_HUMAN (103-538): 1.38e-09: 63.9: 14.25
+	Hs
		782578 HNF4A_HUMAN (88-274): 1.46e-51: 186: 33.85		SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69
+	Hs
		782504 HNF4A_HUMAN (88-274): 1.46e-51: 186: 33.85		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		847122 NR2E1_HUMAN (116-324): 6.69e-47: 171: 29.28		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81