HitPredict

Interactor 1: MAPK2 (P49137)
MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)
Gene: MAPKAPK2

Interactor 2: MK11 (Q15759)
Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)
Gene: MAPK11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 33961781, 35271311, 11551945, 23602568
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 400
Hs

1 364
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Last updated: 15 Jul 2024