Interactor 1: CX3C1 (P49238)
CX3C chemokine receptor 1 (C-X3-C CKR-1) (CX3CR1) (Beta chemokine receptor-like 1) (CMK-BRL-1) (CMK-BRL1) (Fractalkine receptor) (G-protein coupled receptor 13) (V28)
Gene: CX3CR1

Interactor 2: X3CL1 (P78423)
Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine]
Gene: CX3CL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.90 0.833

The method score is based on:

Property Details
Experiments 9931005, 10488147, 9390561, 23125415
Identification Methods x-ray crystallography, experimental interaction detection, saturation binding, solution state nmr, pull down
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~IL8
Common GO terms GO:0002052 - positive regulation of neuroblast proliferation
GO:0002931 - response to ischemia
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0006935 - chemotaxis
and 22 others

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Homologous interactions 0

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Last updated: 15 Jul 2024