HitPredict

Interactor 1: MTR1B (P49286)
Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)
Gene: MTNR1B

Interactor 2: Q60FE5 (Q60FE5)
Filamin A
Gene: FLNA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26514267
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 362 Hs			1 2620
+	Hs
		598007 MTR1B_HUMAN (1-362): 9.76e-84: 260: 100.00		FLNA_HUMAN (1-2620): 0: 2764: 100.00
+	Hs
		428914 ADRB2_HUMAN (1-347): 1.24e-78: 248: 17.55		FLNA_HUMAN (1-2620): 0: 2764: 100.00
+	Hs
		597983 OPRM_HUMAN (5-362): 2.06e-73: 234: 20.39		FLNA_HUMAN (1-2620): 0: 2764: 100.00
+	Hs
		598004 MTR1A_HUMAN (36-354): 2.47e-66: 215: 62.38		FLNA_HUMAN (1-2620): 0: 2764: 100.00
+	Hs
		815890 MTR1A_HUMAN (36-354): 2.47e-66: 215: 62.38		Q60FE5_HUMAN (1-2620): 0: 2764: 100.00
+	Hs
		723009 ADA1B_HUMAN (3-327): 2.24e-76: 245: 22.62		FLNC_HUMAN (11-2620): 0: 1428: 35.90
+	Hs
		722936 ADA1A_HUMAN (19-357): 1.99e-75: 242: 20.75		FLNC_HUMAN (11-2620): 0: 1428: 35.90
+	Hs
		626688 ADA1D_HUMAN (4-319): 1.75e-73: 239: 22.84		FLNC_HUMAN (11-2620): 0: 1428: 35.90
+	Hs
		521497 MTR1B_HUMAN (1-362): 9.76e-84: 260: 100.00		ACTN1_HUMAN (5-432): 4.43e-120: 406: 24.78
+	Hs
		656944 5HT1B_HUMAN (4-329): 4.1e-70: 225: 17.59		ACTN2_HUMAN (5-432): 3.57e-120: 406: 24.78
+	Hs
		521496 MTR1A_HUMAN (36-354): 2.47e-66: 215: 62.38		ACTN1_HUMAN (5-432): 4.43e-120: 406: 24.78
+	Hs
		164552 ADRB2_HUMAN (1-347): 1.24e-78: 248: 17.55		SPTN2_HUMAN (6-318): 3.01e-97: 354: 27.78
+	Hs
		626679 ADA1D_HUMAN (4-319): 1.75e-73: 239: 22.84		UTRN_HUMAN (12-379): 2.01e-96: 352: 24.09
+	Hs
		164572 CCR1_HUMAN (29-357): 1.17e-70: 226: 17.65		SPTN2_HUMAN (6-318): 3.01e-97: 354: 27.78