Interactor 1: CDK8 (P49336)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)
Gene: CDK8

Interactor 2: MED15 (Q96RN5)
Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein)
Gene: MED15

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 24981860, 14657022, 26186194, 26496610, 23749998, 28514442, 29568061, 33961781, 32707033, 20098423, 20720539, 23602568, unassigned1655, 18418385
Identification Methods affinity chromatography technology, proximity labelling technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, tandem affinity purification, ion exchange chromatography
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 464
Hs

1 788
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Rn
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+ Hs
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+ Rn

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Last updated: 15 Jul 2024