Interactor 1: CDK8 (P49336)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)
Gene: CDK8
Interactor 2: MED4 (Q9NPJ6)
Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36)
Gene: MED4
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.759 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25281560, 24981860, 33961781, 35271311, 26186194, 26496610, 28514442, 29568061, 32707033, 23602568, unassigned1655 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016592 - mediator complex |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
