HitPredict - High confidence protein-protein interactions

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	28514442, 33961781, 35271311, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~Cpn60_TCP1
Common GO terms	GO:0002199 - zona pellucida receptor complex GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005832 - chaperonin-containing T-complex and 15 others more... GO:0005874 - microtubule GO:0006457 - protein folding GO:0007339 - binding of sperm to zona pellucida GO:0016887 - ATP hydrolysis activity GO:0032212 - positive regulation of telomere maintenance via telomerase GO:0044183 - protein folding chaperone GO:0044297 - cell body GO:0050821 - protein stabilization GO:0051082 - unfolded protein binding GO:0061077 - chaperone-mediated protein folding GO:0070062 - extracellular exosome GO:0140662 - ATP-dependent protein folding chaperone GO:1904851 - positive regulation of establishment of protein localization to telomere GO:1904871 - positive regulation of protein localization to Cajal body GO:1904874 - positive regulation of telomerase RNA localization to Cajal body
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1	545
Hs

1	539

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Last updated: 15 Jul 2024