HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	33961781, 25342745, 28514442, 27705803, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 342
+	Hs
		903009 TCPH_HUMAN (2-536): 0: 574: 31.18		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		134772 TCPG_HUMAN (1-545): 0: 640: 100.00		PEX7_HUMAN (20-341): 1.26e-56: 188: 18.41
+	Hs
		826904 TCPG_HUMAN (1-545): 0: 640: 100.00		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	Ce
		954082 TCPG_CAEEL (3-536): 0: 599: 60.63		LIN53_CAEEL (10-342): 2.97e-67: 218: 14.88
+	Hs
		1083362 TCPH_HUMAN (2-536): 0: 574: 31.18		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		134793 TCPH_HUMAN (2-536): 0: 574: 31.18		PEX7_HUMAN (20-341): 1.26e-56: 188: 18.41
+	Hs
		1306698 TCPH_HUMAN (2-536): 0: 574: 31.18		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	Hs
		826772 TCPG_HUMAN (1-545): 0: 640: 100.00		POC1A_HUMAN (2-204): 1.46e-29: 118: 18.72
+	Hs
		826601 TCPG_HUMAN (1-545): 0: 640: 100.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		792942 TCPG_HUMAN (1-545): 0: 640: 100.00		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		826784 TCPG_HUMAN (1-545): 0: 640: 100.00		POC1B_HUMAN (6-194): 2.26e-21: 96.4: 8.40
+	Hs
		826847 TCPG_HUMAN (1-545): 0: 640: 100.00		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		826748 TCPG_HUMAN (1-545): 0: 640: 100.00		WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74
+	Hs
		1240450 TCPH_HUMAN (2-536): 0: 574: 31.18		POC1A_HUMAN (2-204): 1.46e-29: 118: 18.72
+	Hs
		903467 TCPH_HUMAN (2-536): 0: 574: 31.18		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	At
		138361 TCPE_ARATH (4-525): 0: 559: 32.26		PEX7_ARATH (124-342): 7.3e-31: 120: 16.23
+	Sc
		760726 TCPG_YEAST (3-530): 0: 575: 58.88		PEX7_YEAST (20-297): 6.62e-22: 97.1: 20.57
+	Hs
		1306704 TCPH_HUMAN (2-536): 0: 574: 31.18		NLE1_HUMAN (249-341): 1.44e-21: 97.2: 15.05
+	Hs
		1306644 TCPH_HUMAN (2-536): 0: 574: 31.18		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		1202777 TCPH_HUMAN (2-536): 0: 574: 31.18		WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74