HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: ACK1 (Q07912)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
Gene: TNK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 1038
+	Hs
		821180 TCPE_HUMAN (4-530): 0: 559: 32.52		ACK1_HUMAN (1-1038): 0: 805: 100.00
+	Hs
		573232 TCPA_HUMAN (10-533): 0: 549: 33.09		ACK1_HUMAN (1-1038): 0: 805: 100.00
+	Hs
		826935 TCPG_HUMAN (1-545): 0: 640: 100.00		ERRFI_HUMAN (445-889): 3.2e-139: 427: 30.21
+	Hs
		433290 TCPG_HUMAN (1-545): 0: 640: 100.00		YES_HUMAN (1-400): 1.3e-128: 403: 29.93
+	Hs
		412086 TCPG_HUMAN (1-545): 0: 640: 100.00		FYN_HUMAN (1-400): 2.52e-126: 397: 30.18
+	Hs
		411642 TCPG_HUMAN (1-545): 0: 640: 100.00		LCK_HUMAN (1-398): 8.72e-125: 391: 30.08
+	Hs
		412325 TCPH_HUMAN (2-536): 0: 574: 31.18		FYN_HUMAN (1-400): 2.52e-126: 397: 30.18
+	Hs
		411833 TCPH_HUMAN (2-536): 0: 574: 31.18		LCK_HUMAN (1-398): 8.72e-125: 391: 30.08
+	Hs
		412084 TCPE_HUMAN (4-530): 0: 559: 32.52		FYN_HUMAN (1-400): 2.52e-126: 397: 30.18
+	Hs
		433248 TCPA_HUMAN (10-533): 0: 549: 33.09		YES_HUMAN (1-400): 1.3e-128: 403: 29.93
+	Hs
		411639 TCPE_HUMAN (4-530): 0: 559: 32.52		LCK_HUMAN (1-398): 8.72e-125: 391: 30.08
+	Hs
		411996 TCPA_HUMAN (10-533): 0: 549: 33.09		FYN_HUMAN (1-400): 2.52e-126: 397: 30.18
+	Hs
		411588 TCPA_HUMAN (10-533): 0: 549: 33.09		LCK_HUMAN (1-398): 8.72e-125: 391: 30.08
+	Hs
		826655 TCPG_HUMAN (1-545): 0: 640: 100.00		PTK6_HUMAN (124-385): 1.48e-49: 184: 40.91
+	Gg
		94466 TCPH_CHICK (2-534): 0: 579: 31.48		KSYK_CHICK (131-381): 2.95e-53: 199: 41.43
+	Hs
		337902 TCPA_HUMAN (10-533): 0: 549: 33.09		EGFR_HUMAN (105-387): 2.98e-55: 211: 39.58
+	Hs
		1046418 TCPH_HUMAN (2-536): 0: 574: 31.18		PTK6_HUMAN (124-385): 1.48e-49: 184: 40.91
+	Hs
		821206 TCPE_HUMAN (4-530): 0: 559: 32.52		PTK6_HUMAN (124-385): 1.48e-49: 184: 40.91
+	Hs
		573257 TCPA_HUMAN (10-533): 0: 549: 33.09		PTK6_HUMAN (124-385): 1.48e-49: 184: 40.91
+	Hs
		411647 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		LCK_HUMAN (1-398): 8.72e-125: 391: 30.08