HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: MK06 (Q16659)
Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
Gene: MAPK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	26972000, 20936779
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 721
+	Hs
		1085489 TCPH_HUMAN (2-536): 0: 574: 31.18		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		821229 TCPE_HUMAN (4-530): 0: 559: 32.52		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		573281 TCPA_HUMAN (10-533): 0: 549: 33.09		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		678541 TCPG_HUMAN (1-545): 0: 640: 100.00		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Rn
		600467 TCPG_RAT (1-545): 0: 639: 97.80		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Hs
		625228 TCPG_HUMAN (1-545): 0: 640: 100.00		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Hs
		678579 TCPH_HUMAN (2-536): 0: 574: 31.18		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Hs
		678540 TCPE_HUMAN (4-530): 0: 559: 32.52		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Hs
		625579 TCPH_HUMAN (2-536): 0: 574: 31.18		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Hs
		573140 TCPA_HUMAN (10-533): 0: 549: 33.09		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Sc
		691051 TCPG_YEAST (3-530): 0: 575: 58.88		HOG1_YEAST (3-374): 5.94e-128: 388: 33.78
+	Hs
		625220 TCPE_HUMAN (4-530): 0: 559: 32.52		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Rn
		600455 TCPE_RAT (4-530): 0: 556: 32.14		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Hs
		573132 TCPA_HUMAN (10-533): 0: 549: 33.09		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Rn
		600336 TCPA_RAT (10-536): 0: 545: 33.27		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Sc
		691072 TCPH_YEAST (5-543): 0: 544: 30.29		HOG1_YEAST (3-374): 5.94e-128: 388: 33.78
+	Hs
		843216 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		MK06_HUMAN (1-721): 0: 638: 100.00
+	Sc
		539365 TCPH_YEAST (5-543): 0: 544: 30.29		KSS1_YEAST (14-338): 3.59e-121: 368: 37.76
+	Hs
		678543 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Hs
		625246 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19