HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25499913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 1298
+	Hs
		826601 TCPG_HUMAN (1-545): 0: 640: 100.00		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		826748 TCPG_HUMAN (1-545): 0: 640: 100.00		WDR5B_HUMAN (5-294): 1.05e-85: 284: 17.38
+	Hs
		826824 TCPG_HUMAN (1-545): 0: 640: 100.00		DCAF5_HUMAN (13-774): 2.83e-71: 260: 14.74
+	Hs
		903467 TCPH_HUMAN (2-536): 0: 574: 31.18		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		1202777 TCPH_HUMAN (2-536): 0: 574: 31.18		WDR5B_HUMAN (5-294): 1.05e-85: 284: 17.38
+	Hs
		821152 TCPE_HUMAN (4-530): 0: 559: 32.52		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		1295340 TCPH_HUMAN (2-536): 0: 574: 31.18		DCAF5_HUMAN (13-774): 2.83e-71: 260: 14.74
+	Cr
		65475 A8II42_CHLRE (3-541): 0: 580: 63.70		MUT11_CHLRE (7-304): 4.26e-71: 244: 15.50
+	Hs
		826772 TCPG_HUMAN (1-545): 0: 640: 100.00		POC1A_HUMAN (83-462): 9.89e-42: 160: 12.69
+	Hs
		792942 TCPG_HUMAN (1-545): 0: 640: 100.00		LIS1_HUMAN (123-346): 3.66e-35: 141: 11.45
+	Hs
		821355 TCPE_HUMAN (4-530): 0: 559: 32.52		SNR40_HUMAN (45-329): 6.16e-55: 197: 11.75
+	Hs
		1240450 TCPH_HUMAN (2-536): 0: 574: 31.18		POC1A_HUMAN (83-462): 9.89e-42: 160: 12.69
+	Hs
		826807 TCPG_HUMAN (1-545): 0: 640: 100.00		FBXW7_HUMAN (164-329): 5.74e-18: 91.8: 9.58
+	Hs
		826784 TCPG_HUMAN (1-545): 0: 640: 100.00		POC1B_HUMAN (1-83): 1.05e-16: 86.8: 16.28
+	Hs
		821316 TCPE_HUMAN (4-530): 0: 559: 32.52		POC1A_HUMAN (83-462): 9.89e-42: 160: 12.69
+	Hs
		826848 TCPG_HUMAN (1-545): 0: 640: 100.00		TBL1Y_HUMAN (5-169): 1.78e-13: 76.7: 21.67
+	Sc
		744617 TCPG_YEAST (3-530): 0: 575: 58.88		TAF5_YEAST (9-127): 1.2e-32: 139: 22.22
+	Hs
		1306654 TCPH_HUMAN (2-536): 0: 574: 31.18		KTNB1_HUMAN (167-610): 7.29e-17: 88: 8.43
+	Hs
		1306645 TCPH_HUMAN (2-536): 0: 574: 31.18		TBL1Y_HUMAN (5-169): 1.78e-13: 76.7: 21.67
+	Hs
		821326 TCPE_HUMAN (4-530): 0: 559: 32.52		POC1B_HUMAN (1-83): 1.05e-16: 86.8: 16.28