HitPredict

Interactor 1: B9EHK7 (B9EHK7)
Homeo box A1 (Homeobox A1)
Gene: Hoxa1

Interactor 2: PBX1 (P41778)
Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1)
Gene: PBX1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	20211142
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Homeobox_KN~Homeodomain
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 336 Mm			1 430
+	Mm
		446928 HXA1_MOUSE (6-336): 4.35e-59: 194: 100.00		PBX1_MOUSE (1-430): 1.17e-150: 436: 100.00
+	Mm
		88435 D3Z4E1_MOUSE (1-119): 1.36e-45: 153: 100.00		PBX1_MOUSE (1-430): 1.17e-150: 436: 100.00
+	Hs
		447226 HXB5_HUMAN (173-305): 8.44e-37: 135: 37.59		PBX1_HUMAN (1-430): 1.17e-150: 436: 100.00
+	Hs
		678886 HXC8_HUMAN (98-297): 4.35e-37: 135: 27.49		PBX1_HUMAN (1-430): 1.17e-150: 436: 100.00
+	Hs
		773059 PDX1_HUMAN (100-312): 1.09e-34: 130: 26.70		PBX1_HUMAN (1-430): 1.17e-150: 436: 100.00
+	Mm
		446929 HXB6_MOUSE (89-307): 9.05e-35: 128: 24.12		PBX1_MOUSE (1-430): 1.17e-150: 436: 100.00
+	Mm
		453082 HXB8_MOUSE (95-321): 1.15e-34: 128: 24.89		PBX1_MOUSE (1-430): 1.17e-150: 436: 100.00
+	Mm
		192602 HXB5_MOUSE (173-305): 7.68e-37: 135: 37.59		PBX3_MOUSE (1-430): 3.78e-143: 417: 81.55
+	Mm
		192605 HXB8_MOUSE (95-321): 1.15e-34: 128: 24.89		PBX3_MOUSE (1-430): 3.78e-143: 417: 81.55
+	Hs
		773100 HXA1_HUMAN (1-336): 2.87e-57: 190: 93.16		PBX2_HUMAN (40-430): 8.92e-118: 352: 80.87
+	Hs
		447227 HXB5_HUMAN (173-305): 8.44e-37: 135: 37.59		PBX2_HUMAN (40-430): 8.92e-118: 352: 80.87
+	Hs
		678887 HXC8_HUMAN (98-297): 4.35e-37: 135: 27.49		PBX2_HUMAN (40-430): 8.92e-118: 352: 80.87
+	Dm
		367183 ANTP_DROME (100-306): 2.51e-45: 160: 32.34		EXD_DROME (3-344): 1.82e-107: 323: 74.07
+	Hs
		538740 HXB2_HUMAN (155-330): 9.24e-39: 142: 30.35		PBX4_HUMAN (42-430): 1.04e-111: 334: 65.13
+	Hs
		447287 HXB5_HUMAN (173-305): 8.44e-37: 135: 37.59		PBX4_HUMAN (42-430): 1.04e-111: 334: 65.13
+	Hs
		678970 HXC8_HUMAN (98-297): 4.35e-37: 135: 27.49		PBX4_HUMAN (42-430): 1.04e-111: 334: 65.13
+	Dm
		428856 DFD_DROME (196-325): 3.26e-35: 136: 39.23		EXD_DROME (3-344): 1.82e-107: 323: 74.07
+	Dm
		447330 SCR_DROME (171-298): 9.96e-36: 135: 37.50		EXD_DROME (3-344): 1.82e-107: 323: 74.07
+	Hs
		829802 HXA1_HUMAN (1-336): 2.87e-57: 190: 93.16		PKNX1_HUMAN (233-370): 6.68e-22: 99.2: 25.71
+	Mm
		678762 HXA2_MOUSE (103-300): 1.81e-34: 131: 30.42		MEIS1_MOUSE (237-320): 6.83e-26: 109: 35.29