HitPredict

Interactor 1: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.908

Property	Details
Experiments	33844281, 17620599, 16709866, 9169477
Identification Methods	affinity chromatography technology, pull down, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Arrestin_C~Clathrin_propel
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 1675
+	Bt
		571840 ARRB1_BOVIN (1-418): 0: 713: 99.04		CLH1_BOVIN (1-1675): 0: 3130: 99.94
+	Hs
		685908 ARRB2_HUMAN (1-407): 0: 626: 76.15		CLH1_HUMAN (1-1675): 0: 3132: 100.00