HitPredict

Interactor 1: B9EKJ1 (B9EKJ1)
Spna2 protein
Gene: Sptan1

Interactor 2: ANK3 (G5E8K5)
Ankyrin-3 (ANK-3) (Ankyrin-G)
Gene: ANK3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36604605
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~EF-hand_7, Ank_2~SH3_1, Spectrin~UPA_2, Spectrin~ZU5
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2477 Mm			1 1961
+	Mm
		103598 Q3UGX2_MOUSE (446-2157): 1.75e-63: 243: 20.31		ANK3_MOUSE (1-1961): 0: 1756: 100.00
+	Mm
		103603 SPTB2_MOUSE (1-1050): 2.4e-34: 147: 20.39		ANK3_MOUSE (1-1961): 0: 1756: 100.00
+	Hs
		360612 SPTA1_HUMAN (2-2477): 2.22e-153: 534: 54.60		ANK1_HUMAN (1-369): 9.47e-89: 324: 34.32
+	Mm
		561172 SPTN1_MOUSE (1-2477): 0: 699: 99.68		ANK2_MOUSE (871-1960): 4.17e-13: 77.7: 9.61
+	Hs
		1021399 SPTN1_HUMAN (1-2477): 0: 699: 98.10		ANK3_HUMAN (791-1955): 1.51e-10: 69.2: 10.06
+	Hs
		965102 SPTN1_HUMAN (1-2477): 0: 699: 98.10		ANK2_HUMAN (844-1949): 1.12e-09: 66.1: 9.22
+	Hs
		556695 SPTB2_HUMAN (1-1050): 4.55e-34: 146: 20.21		ANK1_HUMAN (1-369): 9.47e-89: 324: 34.32
+	Hs
		506803 SPTB1_HUMAN (1847-2417): 1.24e-09: 66.2: 16.93		ANK1_HUMAN (1-369): 9.47e-89: 324: 34.32
+	Rn
		251022 PLEC_RAT (1-1353): 8.73e-42: 172: 10.10		ANK3_RAT (859-1961): 1.31e-40: 168: 23.19
+	Mm
		57416 Q6S385_MOUSE (1-1098): 5.96e-29: 130: 10.44		A2AM57_MOUSE (1-147): 2.08e-35: 150: 23.49
+	Mm
		57440 PLEC_MOUSE (1-1098): 6.35e-29: 130: 10.44		A2AM57_MOUSE (1-147): 2.08e-35: 150: 23.49
+	Hs
		963306 SPTB2_HUMAN (1-1050): 4.55e-34: 146: 20.21		ANK3_HUMAN (791-1955): 1.51e-10: 69.2: 10.06
+	Hs
		963292 SPTB2_HUMAN (1-1050): 4.55e-34: 146: 20.21		ANK2_HUMAN (844-1949): 1.12e-09: 66.1: 9.22
+	Hs
		164611 SPTN2_HUMAN (7-739): 1.32e-29: 132: 22.01		ANK3_HUMAN (791-1955): 1.51e-10: 69.2: 10.06
+	Hs
		164604 SPTN2_HUMAN (7-739): 1.32e-29: 132: 22.01		ANK2_HUMAN (844-1949): 1.12e-09: 66.1: 9.22
+	Hs
		1021404 PLEC_HUMAN (9-1051): 7.32e-27: 123: 11.70		ANK3_HUMAN (791-1955): 1.51e-10: 69.2: 10.06
+	Hs
		211682 ACTN4_HUMAN (1832-2224): 8.83e-10: 66.6: 20.86		ANFY1_HUMAN (2-239): 1.4e-24: 114: 17.89
+	Hs
		965174 MACF1_HUMAN (1048-2375): 8e-18: 93.6: 9.06		ANK2_HUMAN (844-1949): 1.12e-09: 66.1: 9.22
+	Hs
		1021458 SPTN4_HUMAN (1666-1898): 9.89e-15: 83.2: 25.42		ANK3_HUMAN (791-1955): 1.51e-10: 69.2: 10.06