HitPredict

Interactor 1: B9EKJ1 (B9EKJ1)
Spna2 protein
Gene: Sptan1

Interactor 2: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2477 Mm			1 1323
+	Mm
		561157 SPTN1_MOUSE (1-2477): 0: 699: 99.68		TNIK_MOUSE (1-1323): 0: 1277: 100.00
+	Mm
		949310 Q68FG2_MOUSE (11-1617): 4.27e-60: 232: 19.86		TNIK_MOUSE (1-1323): 0: 1277: 100.00
+	Mm
		949304 SPTB2_MOUSE (1-1050): 2.4e-34: 147: 20.39		TNIK_MOUSE (1-1323): 0: 1277: 100.00
+	Mm
		93424 E9Q3P4_MOUSE (1-861): 8.24e-28: 126: 9.58		TNIK_MOUSE (1-1323): 0: 1277: 100.00
+	Mm
		949273 Q155P7_MOUSE (1-861): 1.24e-27: 125: 9.58		TNIK_MOUSE (1-1323): 0: 1277: 100.00
+	Hs
		963449 SPTB2_HUMAN (1-1050): 4.55e-34: 146: 20.21		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Mm
		949420 MACF1_MOUSE (4-816): 2e-12: 75.9: 15.75		TNIK_MOUSE (1-1323): 0: 1277: 100.00
+	Hs
		974168 DYST_HUMAN (1-1502): 2.13e-18: 95.5: 13.60		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Hs
		1356411 MACF1_HUMAN (1048-2375): 8e-18: 93.6: 9.06		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Hs
		1023039 SPTN1_HUMAN (1-2477): 0: 699: 98.10		STK4_HUMAN (5-470): 3.93e-119: 382: 32.59
+	Hs
		1313528 CP250_HUMAN (5-1034): 4.57e-34: 147: 9.98		SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75
+	Hs
		963311 SPTB2_HUMAN (1-1050): 4.55e-34: 146: 20.21		STK3_HUMAN (4-496): 1.39e-117: 377: 30.12
+	Hs
		1344754 MYH2_HUMAN (1694-2462): 4.52e-24: 114: 10.10		SNRK_HUMAN (20-800): 1.21e-124: 406: 15.16
+	Hs
		647985 MACF1_HUMAN (1048-2375): 8e-18: 93.6: 9.06		MARK3_HUMAN (3-717): 6.96e-125: 406: 16.08
+	Hs
		1023137 MYH2_HUMAN (1694-2462): 4.52e-24: 114: 10.10		STK4_HUMAN (5-470): 3.93e-119: 382: 32.59
+	Hs
		521610 ACTN1_HUMAN (1867-2215): 4.37e-11: 70.9: 22.25		SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75
+	Hs
		1027452 MYH2_HUMAN (1694-2462): 4.52e-24: 114: 10.10		STK3_HUMAN (4-496): 1.39e-117: 377: 30.12
+	Hs
		522609 MYH7_HUMAN (1750-2445): 7.6e-21: 103: 10.71		STK4_HUMAN (5-470): 3.93e-119: 382: 32.59
+	Hs
		522610 MYH7_HUMAN (1750-2445): 7.6e-21: 103: 10.71		STK3_HUMAN (4-496): 1.39e-117: 377: 30.12
+	Hs
		974064 DYST_HUMAN (1-1502): 2.13e-18: 95.5: 13.60		STK3_HUMAN (4-496): 1.39e-117: 377: 30.12