HitPredict

Interactor 1: B9EKJ1 (B9EKJ1)
Spna2 protein
Gene: Sptan1

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30562941, 28634551
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization GO:0030864 - cortical actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2477 Mm			1 817
+	Mm
		561163 SPTN1_MOUSE (1-2477): 0: 699: 99.68		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Mm
		1112494 Q3UGX2_MOUSE (446-2157): 1.75e-63: 243: 20.31		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Mm
		1148440 Q68FG2_MOUSE (11-1617): 4.27e-60: 232: 19.86		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Mm
		1143709 SPTB2_MOUSE (1-1050): 2.4e-34: 147: 20.39		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Mm
		1164088 PLEC_MOUSE (1-1098): 6.35e-29: 130: 10.44		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Rn
		88555 D3ZCV0_RAT (1742-2215): 2.62e-12: 74.7: 21.64		NEB2_RAT (1-817): 2.42e-118: 379: 98.90
+	Mm
		1164079 ACTN2_MOUSE (1742-2215): 2.93e-13: 77.8: 21.48		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Rn
		192529 ACTN1_RAT (1867-2215): 2.58e-11: 71.6: 22.51		NEB2_RAT (1-817): 2.42e-118: 379: 98.90
+	Mm
		1163959 ACTN1_MOUSE (1867-2215): 2.7e-10: 68.2: 21.99		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Mm
		885082 ACTN4_MOUSE (1848-2224): 7.46e-10: 66.6: 20.30		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Hs
		297818 K0754_HUMAN (4-1482): 1.82e-63: 244: 14.02		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		1256956 CP250_HUMAN (5-1034): 4.57e-34: 147: 9.98		PAR3L_HUMAN (159-758): 1.59e-43: 172: 15.59
+	Mm
		1143324 SPTB2_MOUSE (1-1050): 2.4e-34: 147: 20.39		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Hs
		876385 GOGB1_HUMAN (1455-2436): 7.45e-20: 100: 8.67		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		876363 DYST_HUMAN (1-1502): 2.13e-18: 95.5: 13.60		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Mm
		1143539 MACF1_MOUSE (4-816): 2e-12: 75.9: 15.75		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Hs
		521581 ACTN1_HUMAN (1867-2215): 4.37e-11: 70.9: 22.25		LNX1_HUMAN (224-773): 4.36e-33: 138: 11.92
+	Mm
		885081 ACTN4_MOUSE (1848-2224): 7.46e-10: 66.6: 20.30		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Hs
		521598 ACTN1_HUMAN (1867-2215): 4.37e-11: 70.9: 22.25		MAGI1_HUMAN (449-794): 5.95e-16: 84.7: 12.50
+	Dm
		1182586 Q7KV70_DROME (1670-2164): 3.21e-10: 68.6: 16.30		PATJ_DROME (493-582): 1.47e-11: 70.4: 31.11