HitPredict

Interactor 1: B9EKJ1 (B9EKJ1)
Spna2 protein
Gene: Sptan1

Interactor 2: CNKR2 (Q80YA9)
Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)
Gene: Cnksr2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2477 Mm			1 1032
+	Mm
		561168 SPTN1_MOUSE (1-2477): 0: 699: 99.68		CNKR2_MOUSE (1-1032): 0: 1015: 100.00
+	Mm
		1148443 Q68FG2_MOUSE (11-1617): 4.27e-60: 232: 19.86		CNKR2_MOUSE (1-1032): 0: 1015: 100.00
+	Mm
		1143715 SPTB2_MOUSE (1-1050): 2.4e-34: 147: 20.39		CNKR2_MOUSE (1-1032): 0: 1015: 100.00
+	Hs
		1045526 SPTN1_HUMAN (1-2477): 0: 699: 98.10		PKHA5_HUMAN (445-1031): 8.91e-61: 228: 15.51
+	Hs
		1045520 SPTN1_HUMAN (1-2477): 0: 699: 98.10		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		1313532 CP250_HUMAN (5-1034): 4.57e-34: 147: 9.98		PKHA5_HUMAN (445-1031): 8.91e-61: 228: 15.51
+	Hs
		963422 SPTB2_HUMAN (1-1050): 4.55e-34: 146: 20.21		PKHA5_HUMAN (445-1031): 8.91e-61: 228: 15.51
+	Hs
		1068669 PLEC_HUMAN (9-1051): 7.32e-27: 123: 11.70		PKHA5_HUMAN (445-1031): 8.91e-61: 228: 15.51
+	Hs
		963417 SPTB2_HUMAN (1-1050): 4.55e-34: 146: 20.21		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Dm
		527098 SPTCA_DROME (2-1479): 5.28e-35: 150: 19.77		Q7KV70_DROME (532-788): 4.13e-40: 164: 19.65
+	Dm
		527093 SPTCA_DROME (2-1479): 5.28e-35: 150: 19.77		Q23980_DROME (532-788): 1.52e-38: 158: 19.65
+	Dm
		54298 A1Z9J2_DROME (1-742): 2.93e-31: 137: 16.99		Q7KV70_DROME (532-788): 4.13e-40: 164: 19.65
+	Hs
		1068666 PLEC_HUMAN (9-1051): 7.32e-27: 123: 11.70		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		1059270 GOGB1_HUMAN (1455-2436): 7.45e-20: 100: 8.67		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		521561 ACTN1_HUMAN (1867-2215): 4.37e-11: 70.9: 22.25		PKHA7_HUMAN (446-953): 3.62e-53: 204: 14.99
+	Hs
		211598 ACTN4_HUMAN (1832-2224): 8.83e-10: 66.6: 20.86		PKHA7_HUMAN (446-953): 3.62e-53: 204: 14.99
+	Hs
		974145 DYST_HUMAN (1-1502): 2.13e-18: 95.5: 13.60		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		1331636 MACF1_HUMAN (1048-2375): 8e-18: 93.6: 9.06		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		521613 ACTN1_HUMAN (1867-2215): 4.37e-11: 70.9: 22.25		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		521598 ACTN1_HUMAN (1867-2215): 4.37e-11: 70.9: 22.25		MAGI1_HUMAN (205-563): 1.67e-11: 70.9: 14.13