HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 1590
+	Hs
		846743 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Hs
		846921 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		846989 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		229341 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	Hs
		658641 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		SMCA1_HUMAN (618-1559): 0: 797: 28.00
+	Hs
		229359 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	Mm
		935460 H31_MOUSE (5-134): 1.29e-52: 164: 48.86		SMCA5_MOUSE (613-1584): 0: 803: 27.51
+	Hs
		658647 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SMCA1_HUMAN (618-1559): 0: 797: 28.00
+	Hs
		934770 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CHD4_HUMAN (370-1589): 0: 749: 22.31
+	Hs
		1059646 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		CHD4_HUMAN (370-1589): 0: 749: 22.31
+	Hs
		1059677 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		CHD4_HUMAN (370-1589): 0: 749: 22.31
+	Hs
		935262 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CHD8_HUMAN (19-1359): 0: 741: 21.67
+	Hs
		828213 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		CHD3_HUMAN (415-1590): 0: 725: 23.92
+	Hs
		934705 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CHD3_HUMAN (415-1590): 0: 725: 23.92
+	Hs
		828310 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		CHD6_HUMAN (315-1363): 0: 711: 24.12
+	Hs
		935016 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CHD5_HUMAN (409-1588): 0: 718: 22.36
+	Hs
		935014 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CHD6_HUMAN (315-1363): 0: 711: 24.12
+	Hs
		1086232 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		CHD6_HUMAN (315-1363): 0: 711: 24.12
+	Hs
		828410 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		CHD7_HUMAN (123-733): 1.37e-11: 72.1: 7.20
+	Hs
		935324 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CHD7_HUMAN (123-733): 1.37e-11: 72.1: 7.20