HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	28514442, 34079125, 16622419
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 709
+	Hs
		934695 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		828385 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		935263 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		935143 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CIC_HUMAN (424-708): 7.87e-39: 157: 16.49
+	Hs
		1157221 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		CIC_HUMAN (424-708): 7.87e-39: 157: 16.49
+	Hs
		869809 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23
+	Hs
		818788 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15
+	Hs
		727874 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96
+	Hs
		617322 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		SP100_HUMAN (486-629): 1.52e-24: 111: 28.86
+	Hs
		643268 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449604 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04
+	Hs
		643320 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		567659 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52
+	Hs
		449665 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04
+	Hs
		643358 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449756 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04
+	Hs
		567673 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52
+	Hs
		567719 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52
+	Hs
		935035 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB4_HUMAN (546-635): 1.8e-11: 65.5: 27.17
+	Hs
		175769 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB3_HUMAN (551-696): 3.34e-11: 65.2: 22.58