Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: HJURP (Q8NCD3)
Holliday junction recognition protein (14-3-3-associated AKT substrate) (Fetal liver-expressing gene 1 protein) (Up-regulated in lung cancer 9)
Gene: HJURP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.90 0.937

The method score is based on:

Property Details
Experiments 25727006, 19410545, 19410544, 21478274, 20080577, 22406139, 26496610, 28514442, 31550462, 34079125, 33961781, 35271311, 16622419
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Histone~Scm3
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0034080 - CENP-A containing chromatin assembly
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024