HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: KDM2B (Q8NHM5)
Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B)
Gene: KDM2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 1336
+	Hs
		935008 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		KDM2B_HUMAN (1-1336): 0: 1220: 100.00
+	Hs
		1174601 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		KDM2B_HUMAN (1-1336): 0: 1220: 100.00
+	Hs
		952482 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		KDM2B_HUMAN (1-1336): 0: 1220: 100.00
+	Hs
		828422 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Hs
		935373 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Hs
		1086352 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Hs
		1157239 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Hs
		952701 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Dm
		356110 H3_DROME (5-134): 1.73e-51: 161: 48.86		JHD1_DROME (46-1233): 0: 600: 24.77
+	Hs
		256390 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Hs
		256400 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Hs
		256412 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Hs
		256401 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Hs
		256416 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Ce
		445734 H3_CAEEL (5-134): 3.34e-51: 161: 47.33		KDM7_CAEEL (22-553): 8.84e-164: 515: 24.73
+	Hs
		828427 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		935393 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		1086360 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		1174697 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		1174674 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		CXXC1_HUMAN (607-651): 5.77e-09: 62.4: 58.70