HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: CBX8 (Q9HC52)
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)
Gene: CBX8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15009096
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 389
+	Hs
		935259 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX8_HUMAN (1-389): 5.01e-104: 314: 100.00
+	Hs
		935387 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CDYL_HUMAN (2-312): 1.24e-66: 223: 14.65
+	Hs
		316000 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX6_HUMAN (1-386): 1.08e-65: 216: 33.26
+	Hs
		316040 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		CBX6_HUMAN (1-386): 1.08e-65: 216: 33.26
+	Hs
		123231 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX4_HUMAN (1-349): 3.84e-62: 210: 21.93
+	Hs
		123254 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		CBX4_HUMAN (1-349): 3.84e-62: 210: 21.93
+	Hs
		935156 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		MPP8_HUMAN (6-356): 2.27e-52: 188: 18.85
+	Hs
		828230 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		CBX2_HUMAN (2-348): 3.75e-46: 167: 22.03
+	Hs
		934768 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX2_HUMAN (2-348): 3.75e-46: 167: 22.03
+	Hs
		327837 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX7_HUMAN (1-235): 2.71e-41: 147: 28.46
+	Hs
		934987 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CDYL2_HUMAN (9-312): 9.92e-33: 130: 12.81
+	Hs
		828217 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		CBX3_HUMAN (9-144): 1.3e-26: 106: 25.74
+	Hs
		203659 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SUV91_HUMAN (11-102): 9.92e-27: 112: 25.25
+	Hs
		800317 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		CBX5_HUMAN (11-144): 1.06e-25: 104: 25.00
+	Hs
		203711 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		SUV91_HUMAN (11-102): 9.92e-27: 112: 25.25
+	Hs
		935237 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SUV92_HUMAN (9-103): 2.94e-26: 110: 22.43
+	Hs
		934721 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX3_HUMAN (9-144): 1.3e-26: 106: 25.74
+	Hs
		800341 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX5_HUMAN (11-144): 1.06e-25: 104: 25.00
+	Hs
		934657 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CBX1_HUMAN (17-122): 3.63e-23: 97.5: 28.97
+	Mm
		935445 H31_MOUSE (5-134): 1.29e-52: 164: 48.86		CBX1_MOUSE (17-122): 3.63e-23: 97.5: 28.97