HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 601
+	Hs
		935342 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGX4_HUMAN (1-601): 0: 813: 100.00
+	Hs
		1086344 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		HMGX4_HUMAN (1-601): 0: 813: 100.00
+	Hs
		828285 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		934930 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		1086201 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		727874 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		SOX6_HUMAN (320-556): 1.34e-33: 138: 17.05
+	Hs
		818788 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SOX9_HUMAN (337-527): 1.69e-32: 133: 14.43
+	Hs
		828208 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		934695 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		449604 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		643268 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		449665 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		449756 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		643320 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		643358 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		617322 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		SP100_HUMAN (388-490): 1.64e-16: 85.3: 30.48
+	Hs
		935143 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		1157221 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		935035 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB4_HUMAN (387-499): 1.93e-12: 68: 15.93
+	Hs
		175769 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HMGB3_HUMAN (411-495): 5.79e-12: 67.2: 21.84