HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: PHF8 (Q9UPP1)
Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8)
Gene: PHF8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 1060
+	Hs
		935373 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PHF8_HUMAN (1-1060): 0: 1403: 100.00
+	Hs
		1086352 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		PHF8_HUMAN (1-1060): 0: 1403: 100.00
+	Hs
		1157239 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		PHF8_HUMAN (1-1060): 0: 1403: 100.00
+	Hs
		256390 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		256400 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		256412 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		256416 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		828427 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		935393 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		1086360 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		828308 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Hs
		935008 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Hs
		1174601 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Ce
		445734 H3_CAEEL (5-134): 3.34e-51: 161: 47.33		KDM7_CAEEL (23-585): 0: 554: 25.23
+	Hs
		828212 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		934702 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		1017307 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		1017316 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		935185 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43
+	Hs
		1086300 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43