HitPredict

Interactor 1: UBE2A (P49459)
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)
Gene: UBE2A

Interactor 2: UBE2A (P49459)
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)
Gene: UBE2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.896

The method score is based on:

Property Details
Experiments 25582440, 30700555, 36162503, 20061386
Identification Methods enzymatic study, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~UQ_con
Common GO terms GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000209 - protein polyubiquitination
GO:0000785 - chromatin
GO:0004842 - ubiquitin-protein transferase activity
GO:0005524 - ATP binding
and 15 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 152
Hs

1 152
+ Hs
+ Zm
+ Zm
+ Hs
+ Hs
+ Zm
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ Zm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024