HitPredict

Interactor 1: UBE2A (P49459)
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)
Gene: UBE2A

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26489670
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_5
Common GO terms	GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 1133
+	Hs
		919745 UB2D2_HUMAN (5-149): 7.73e-78: 229: 38.62		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		927756 UBE2B_HUMAN (1-151): 3.28e-74: 219: 96.03		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		919868 UB2D2_HUMAN (5-149): 7.73e-78: 229: 38.62		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		927778 UBE2B_HUMAN (1-151): 3.28e-74: 219: 96.03		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1297369 UB2E2_HUMAN (3-150): 6.19e-73: 218: 35.14		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1282349 UB2E3_HUMAN (3-150): 2.3e-72: 217: 35.14		RC3H2_HUMAN (1-1107): 0: 1494: 51.72