Interactor 1: UBE2A (P49459)
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)
Gene: UBE2A
Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.991 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22904075, 26496610, 26170230, 27377895, 10908344, 10884424, 31887036, 24981860, 18363965, 21858012, 18926833, 22456510, 17108083, 24672041, 25582440, 19549727, 15359278, 21967848, 15509568, 25023518 |
| Identification Methods | pull down, affinity chromatography technology, two hybrid, fluorescent resonance energy transfer, enzymatic study, anti tag coimmunoprecipitation, two hybrid array, tandem affinity purification |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UQ_con~zf-C3HC4_2 |
| Common GO terms | GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006301 - postreplication repair GO:0031625 - ubiquitin protein ligase binding |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
