HitPredict

Interactor 1: MAD2 (P40958)
Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)
Gene: MAD2

Interactor 2: MAD2 (P40958)
Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)
Gene: MAD2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.907

The method score is based on:

Property	Details
Experiments	23000150, 16818718, 17634282, 19143472, 39079532
Identification Methods	affinity chromatography technology, biochemical, two hybrid, pull down
Interaction Type	physical association, association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	HORMA~HORMA
Common GO terms	GO:0000776 - kinetochore GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0007094 - mitotic spindle assembly checkpoint signaling GO:0033597 - mitotic checkpoint complex and 4 others more... GO:0044774 - mitotic DNA integrity checkpoint signaling GO:0051301 - cell division GO:1902499 - positive regulation of protein autoubiquitination GO:1990333 - mitotic checkpoint complex, CDC20-MAD2 subcomplex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	196
Sc

1	196

Service provided by Combinatics, Japan

Last updated: 11Aug2025