Interactor 1: PRI1 (P49642)
DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49)
Gene: PRIM1

Interactor 2: PRI2 (P49643)
DNA primase large subunit (DNA primase 58 kDa subunit) (p58)
Gene: PRIM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 28757209, 32296183, 28514442, 33961781, unassigned1304
Identification Methods pull down, two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_primase_S~DNA_primase_lrg
Common GO terms GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0006269 - DNA replication, synthesis of primer
GO:0006270 - DNA replication initiation
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 420
Hs

1 509
+ Dm
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024