HitPredict

Interactor 1: MNB (P49657)
Serine/threonine-protein kinase minibrain (EC 2.7.12.1)
Gene: MNB

Interactor 2: Q9VR53 (Q9VR53)
LD15927p (Wings apart, isoform A) (Wings apart, isoform B) (Wings apart, isoform C) (Wings apart, isoform D)
Gene: wap

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	23955303, 22036573
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0035331 - negative regulation of hippo signaling GO:0045927 - positive regulation of growth GO:0046622 - positive regulation of organ growth
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 908 Dm			1 343
+	Hs
		902911 DYR1A_HUMAN (7-689): 1.04e-139: 436: 54.27		DCAF7_HUMAN (3-343): 1.12e-82: 256: 85.38
+	Hs
		997716 DYR1A_HUMAN (7-689): 1.04e-139: 436: 54.27		RBBP4_HUMAN (11-343): 2.56e-72: 231: 13.23
+	Hs
		903063 DYR1B_HUMAN (48-683): 4.79e-131: 409: 52.82		DCAF7_HUMAN (3-343): 1.12e-82: 256: 85.38
+	Hs
		625294 CDK2_HUMAN (161-495): 8.4e-128: 388: 27.19		DCAF7_HUMAN (3-343): 1.12e-82: 256: 85.38
+	Hs
		302287 DYR1A_HUMAN (7-689): 1.04e-139: 436: 54.27		SC31A_HUMAN (24-343): 7.17e-59: 206: 18.45
+	Sc
		539289 YAK1_YEAST (83-559): 8.27e-125: 398: 30.69		YP247_YEAST (9-343): 2.98e-75: 242: 32.30
+	Hs
		902983 DYRK2_HUMAN (60-546): 3.88e-122: 384: 33.47		DCAF7_HUMAN (3-343): 1.12e-82: 256: 85.38
+	Ce
		1259285 MBK1_CAEEL (36-576): 2.2e-123: 396: 48.63		Q93759_CAEEL (7-343): 9.47e-73: 234: 63.37
+	Hs
		997923 DYRK4_HUMAN (129-588): 1.68e-122: 382: 34.74		RBBP4_HUMAN (11-343): 2.56e-72: 231: 13.23
+	Sp
		251855 PPK15_SCHPO (61-528): 6.51e-123: 384: 33.06		YBE8_SCHPO (9-343): 1.03e-70: 228: 34.82
+	At
		1105866 KSG7_ARATH (132-540): 1.66e-121: 375: 24.47		TTG1_ARATH (2-343): 7.25e-73: 230: 49.71
+	Hs
		1044099 DYR1A_HUMAN (7-689): 1.04e-139: 436: 54.27		GRWD1_HUMAN (126-327): 2.27e-22: 99: 22.83
+	Hs
		625202 CDK2_HUMAN (161-495): 8.4e-128: 388: 27.19		LIS1_HUMAN (151-341): 7.17e-39: 144: 13.09
+	Hs
		414806 CDK1_HUMAN (161-487): 6.91e-122: 373: 25.67		LIS1_HUMAN (151-341): 7.17e-39: 144: 13.09
+	Hs
		903402 DYRK2_HUMAN (60-546): 3.88e-122: 384: 33.47		WDR5_HUMAN (208-343): 3.14e-30: 119: 13.97
+	Hs
		1319415 DYRK4_HUMAN (129-588): 1.68e-122: 382: 34.74		WDR33_HUMAN (221-342): 9.82e-17: 83.3: 13.93
+	Hs
		903022 HIPK2_HUMAN (162-487): 2.41e-52: 201: 38.30		DCAF7_HUMAN (3-343): 1.12e-82: 256: 85.38
+	Hs
		196977 CLK2_HUMAN (146-493): 5.92e-50: 186: 30.83		PRP4_HUMAN (119-343): 1.64e-44: 161: 15.65
+	Hs
		833971 CLK2_HUMAN (146-493): 5.92e-50: 186: 30.83		WDR33_HUMAN (221-342): 9.82e-17: 83.3: 13.93