HitPredict

Interactor 1: KC1E (P49674)
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)
Gene: CSNK1E

Interactor 2: PER3 (P56645)
Period circadian protein homolog 3 (hPER3) (Cell growth-inhibiting gene 13 protein) (Circadian clock protein PERIOD 3)
Gene: PER3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14701732
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0032922 - circadian regulation of gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 416 Hs			1 1201
+	Mm
		1337560 KC1E_MOUSE (1-416): 8.22e-136: 397: 98.80		BMAL1_MOUSE (16-521): 1.1e-106: 351: 17.99
+	Hs
		822275 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		HIF1A_HUMAN (23-758): 1.45e-114: 378: 11.45
+	Hs
		165951 KC1E_HUMAN (1-416): 1.42e-136: 399: 100.00		PER2_HUMAN (13-1200): 2.35e-100: 348: 32.51
+	Hs
		126110 KC1E_HUMAN (1-416): 1.42e-136: 399: 100.00		BMAL1_HUMAN (16-521): 4.95e-103: 341: 17.95
+	Hs
		681876 AKT1_HUMAN (5-356): 7.92e-119: 356: 18.56		HIF1A_HUMAN (23-758): 1.45e-114: 378: 11.45
+	Hs
		165949 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		PER2_HUMAN (13-1200): 2.35e-100: 348: 32.51
+	Mm
		222713 KC1E_MOUSE (1-416): 8.22e-136: 397: 98.80		PER2_MOUSE (13-1201): 2.93e-89: 316: 30.50
+	Mm
		222703 KC1A_MOUSE (2-326): 1.03e-134: 391: 69.54		PER2_MOUSE (13-1201): 2.93e-89: 316: 30.50
+	Mm
		139877 KC1E_MOUSE (1-416): 8.22e-136: 397: 98.80		CLOCK_MOUSE (11-831): 1.8e-83: 293: 12.04
+	Dm
		429417 KC1A_DROME (2-321): 9.31e-123: 361: 64.38		PER_DROME (131-1094): 8.07e-94: 329: 16.91
+	Mm
		222711 KC1D_MOUSE (1-406): 1.2e-125: 371: 83.50		PER2_MOUSE (13-1201): 2.93e-89: 316: 30.50
+	Hs
		181505 KC1E_HUMAN (1-416): 1.42e-136: 399: 100.00		CLOCK_HUMAN (11-817): 7.42e-79: 279: 12.38
+	Hs
		182326 KC1E_HUMAN (1-416): 1.42e-136: 399: 100.00		PER1_HUMAN (28-1184): 8.92e-74: 270: 31.57
+	Mm
		193662 KC1E_MOUSE (1-416): 8.22e-136: 397: 98.80		PER1_MOUSE (28-1184): 1.25e-70: 261: 29.68
+	Mm
		193658 KC1A_MOUSE (2-326): 1.03e-134: 391: 69.54		PER1_MOUSE (28-1184): 1.25e-70: 261: 29.68
+	Hs
		649042 AKT1_HUMAN (5-356): 7.92e-119: 356: 18.56		ARNT_HUMAN (4-637): 3.35e-84: 294: 14.49
+	Hs
		182324 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		PER1_HUMAN (28-1184): 8.92e-74: 270: 31.57
+	Mm
		193661 KC1D_MOUSE (1-406): 1.2e-125: 371: 83.50		PER1_MOUSE (28-1184): 1.25e-70: 261: 29.68
+	Hs
		182338 KC1G2_HUMAN (3-348): 3.73e-119: 354: 50.28		PER1_HUMAN (28-1184): 8.92e-74: 270: 31.57
+	Dm
		247701 DCO_DROME (1-339): 2.92e-115: 345: 77.29		CLOCK_DROME (46-714): 2.72e-28: 125: 15.62