HitPredict

Interactor 1: KC1E (P49674)
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)
Gene: CSNK1E

Interactor 2: CRY1 (Q16526)
Cryptochrome-1
Gene: CRY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	23555304, 26496610, 28514442, 33961781, 35271311, 23455922
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0032922 - circadian regulation of gene expression GO:0042752 - regulation of circadian rhythm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 586
+	Mm
		956910 KC1E_MOUSE (1-416): 8.22e-136: 397: 98.80		CRY1_MOUSE (1-586): 0: 819: 93.23
+	Mm
		956904 KC1A_MOUSE (2-326): 1.03e-134: 391: 69.54		CRY1_MOUSE (1-586): 0: 819: 93.23
+	Hs
		822272 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		CRY1_HUMAN (1-586): 0: 811: 100.00
+	Mm
		1206798 KC1A_MOUSE (2-326): 1.03e-134: 391: 69.54		CRY2_MOUSE (2-531): 0: 692: 78.11
+	Hs
		830380 KC1E_HUMAN (1-416): 1.42e-136: 399: 100.00		CRY2_HUMAN (3-519): 0: 676: 79.11
+	Hs
		822280 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		CRY2_HUMAN (3-519): 0: 676: 79.11
+	At
		1275559 CKL3_ARATH (1-412): 4.55e-122: 362: 51.08		CRY2_ARATH (1-492): 0: 540: 25.30
+	At
		1228208 CKL4_ARATH (1-408): 4.71e-120: 356: 52.21		CRY2_ARATH (1-492): 0: 540: 25.30