HitPredict

Interactor 1: KC1E (P49674)
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)
Gene: CSNK1E

Interactor 2: MICU2 (Q8IYU8)
Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1)
Gene: MICU2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 434
+	Hs
		822315 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		MICU2_HUMAN (1-434): 1.79e-175: 499: 100.00
+	Hs
		822193 KC1A_HUMAN (2-326): 1.03e-134: 391: 69.54		S2513_HUMAN (74-408): 5.24e-81: 264: 16.29
+	At
		626341 CKL11_ARATH (1-415): 8.33e-119: 355: 52.67		CML12_ARATH (57-276): 2.11e-16: 81.7: 14.46
+	Hs
		483926 KCC2B_HUMAN (4-396): 1.37e-118: 361: 16.91		CALM1_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		484000 KCC2B_HUMAN (4-396): 1.37e-118: 361: 16.91		CALM2_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		484118 KCC2B_HUMAN (4-396): 1.37e-118: 361: 16.91		CALM3_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		483927 KCC2G_HUMAN (4-411): 4.92e-119: 359: 16.31		CALM1_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		484001 KCC2G_HUMAN (4-411): 4.92e-119: 359: 16.31		CALM2_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		484119 KCC2G_HUMAN (4-411): 4.92e-119: 359: 16.31		CALM3_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		483928 KCC2D_HUMAN (4-339): 1.58e-119: 358: 16.62		CALM1_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		484002 KCC2D_HUMAN (4-339): 1.58e-119: 358: 16.62		CALM2_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Hs
		484120 KCC2D_HUMAN (4-339): 1.58e-119: 358: 16.62		CALM3_HUMAN (151-259): 2.03e-13: 69.4: 17.86
+	Dm
		906661 KCC2A_DROME (4-372): 1.67e-119: 359: 15.43		CALM_DROME (151-259): 5.46e-13: 68.2: 17.86
+	At
		188307 CKL11_ARATH (1-415): 8.33e-119: 355: 52.67		CML8_ARATH (119-259): 1.48e-12: 67.1: 18.75
+	At
		483080 CKL11_ARATH (1-415): 8.33e-119: 355: 52.67		CALM4_ARATH (151-256): 3.93e-12: 65.5: 18.35
+	At
		886546 CKL11_ARATH (1-415): 8.33e-119: 355: 52.67		CALM7_ARATH (151-256): 6.5e-12: 65.2: 18.35
+	Hs
		648497 KCC2G_HUMAN (4-411): 4.92e-119: 359: 16.31		CALL3_HUMAN (151-256): 1.53e-10: 60.9: 16.51
+	At
		976623 CKL11_ARATH (1-415): 8.33e-119: 355: 52.67		CALM6_ARATH (151-256): 1.08e-11: 64.4: 18.35