HitPredict

Interactor 1: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Interactor 2: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.888

The method score is based on:

Property Details
Experiments 17897945, 20310066, 19805193, 27194810
Identification Methods pull down, x-ray crystallography, two hybrid array
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Nucleoporin2~Nucleoporin2, Nup96~Nup96
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003723 - RNA binding
GO:0005643 - nuclear pore
GO:0006302 - double-strand break repair
and 18 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1317
Sc

1 1317
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs
+ Tt
+ Ce
+ Hs
+ Tt
+ Hs
+ Ce
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024