HitPredict

Interactor 1: CTCF (P49711)
Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)
Gene: CTCF

Interactor 2: PURA (Q00577)
Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)
Gene: PURA

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	34591612
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 727 Hs			1 322
+	Hs
		831074 CTCF_HUMAN (1-727): 0: 637: 100.00		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		1251656 ZN420_HUMAN (91-569): 0: 549: 23.83		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		983764 ZNF91_HUMAN (124-719): 5.44e-175: 534: 19.50		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		977980 ZNF92_HUMAN (341-727): 4.72e-152: 456: 18.73		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		563277 ZN708_HUMAN (343-710): 3.82e-130: 398: 20.75		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		1305553 ZN184_HUMAN (433-719): 3.26e-114: 363: 17.29		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		563768 ZNF28_HUMAN (390-719): 4.05e-104: 335: 18.64		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		960572 ZNF71_HUMAN (176-402): 4.24e-58: 206: 24.67		PURA_HUMAN (1-322): 1.72e-144: 411: 100.00
+	Hs
		997503 ZN616_HUMAN (577-716): 4.88e-33: 138: 4.73		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		67878 ZN724_HUMAN (122-239): 2.3e-22: 104: 5.39		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22
+	Hs
		1294639 ZN845_HUMAN (574-715): 3.28e-20: 97.9: 6.00		PURG_HUMAN (51-301): 2.2e-105: 313: 53.22