HitPredict

Interactor 1: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	34189442
Identification Methods	proximity labelling technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Hs			1 1214
+	Hs
		831547 CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		569890 CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		569936 CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		232052 CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Mm
		862837 CEBPA_MOUSE (1-358): 4.3e-64: 209: 91.19		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Hs
		831855 CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261438 CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		231994 CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		570236 CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261397 CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		831502 CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Mm
		70906 CEBPA_MOUSE (1-358): 4.3e-64: 209: 91.19		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78
+	Hs
		569452 CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61		SC24C_HUMAN (1005-1213): 5.27e-13: 75.8: 19.28
+	Hs
		297849 CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61		SC24D_HUMAN (951-1204): 5.56e-13: 75.7: 25.44
+	Mm
		70898 CEBPB_MOUSE (55-357): 1.43e-33: 127: 30.36		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78
+	Mm
		70890 ATF2_MOUSE (46-352): 5.9e-26: 110: 10.97		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78
+	Mm
		1351630 PCLO_MOUSE (18-252): 8.14e-11: 65.9: 14.77		PCLO_MOUSE (643-1196): 2.88e-11: 70.5: 9.26
+	Hs
		302269 SC24C_HUMAN (15-284): 7.83e-12: 68.6: 11.43		SC31A_HUMAN (741-1068): 3.97e-10: 66.6: 9.06
+	Hs
		297843 SC24D_HUMAN (17-228): 1.75e-09: 61.3: 11.32		SC31A_HUMAN (741-1068): 3.97e-10: 66.6: 9.06
+	Dm
		113976 M9PB30_DROME (2-286): 9.11e-09: 59.4: 12.67		M9PB30_DROME (665-1213): 3.26e-09: 63.9: 9.40