HitPredict

Interactor 1: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)
Gene: PSMB2

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35271311, 35858375
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Hs			1 156
+	Hs
		638108 PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924123 PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		594505 PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	At
		188707 PSB2A_ARATH (1-190): 4.76e-78: 233: 45.79		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		189245 PSB2B_ARATH (1-190): 7.56e-77: 230: 45.26		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Rn
		656805 PSB5_RAT (2-197): 2.34e-68: 211: 17.86		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		832088 PSB2_HUMAN (1-201): 5.46e-65: 200: 100.00		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	At
		188713 PSB5A_ARATH (2-198): 1.26e-67: 209: 21.83		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		286456 PSA4A_ARATH (3-198): 7.11e-68: 209: 21.68		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Rn
		566254 PSA2_RAT (4-197): 1.12e-64: 201: 17.86		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	At
		1092123 PSB5B_ARATH (2-198): 6.83e-67: 208: 21.83		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		188696 PSA2A_ARATH (2-197): 1.83e-66: 205: 18.09		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		1091773 PSA2B_ARATH (2-197): 1.6e-65: 203: 18.09		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		474931 PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Hs
		474930 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		1091724 PSB7B_ARATH (3-198): 1.02e-63: 199: 18.88		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		188702 PSB7A_ARATH (3-198): 1.31e-63: 199: 18.88		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		189234 PSA7B_ARATH (4-196): 8.87e-64: 199: 16.16		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		1091802 PSB6_ARATH (3-190): 2.37e-49: 162: 18.09		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Zm
		35350 A0A1D6LKR2_MAIZE (3-190): 9.29e-47: 155: 17.71		Q41754_MAIZE (1-76): 1.28e-34: 125: 96.05