HitPredict

Interactor 1: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)
Gene: PSMB2

Interactor 2: ECM29 (Q5VYK3)
Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog)
Gene: ECPAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32723828, 35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 1845
+	Hs
		656731 PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		1139426 PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		638148 PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		637703 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		594558 PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Sc
		604793 PSB4_YEAST (1-193): 1.25e-78: 235: 44.85		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Sc
		675414 PSB5_YEAST (2-198): 7.84e-67: 208: 17.77		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Sc
		751158 PSB1_YEAST (3-191): 5.03e-57: 180: 20.64		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Sc
		625930 PSB2_YEAST (3-184): 1.28e-46: 155: 17.03		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Hs
		637714 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		CAND1_HUMAN (282-1301): 2.08e-34: 146: 12.77
+	Sc
		560901 PSB4_YEAST (1-193): 1.25e-78: 235: 44.85		EF3A_YEAST (1093-1349): 9.8e-14: 79.2: 17.11