HitPredict

Interactor 1: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)
Gene: PSMB2

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	22119785, 32614325
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 643
+	Hs
		656791 PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86		AMFR_HUMAN (1-643): 0: 593: 100.00
+	Hs
		1303493 PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80		AMFR_HUMAN (1-643): 0: 593: 100.00
+	Hs
		638214 PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73		AMFR_HUMAN (1-643): 0: 593: 100.00
+	Hs
		637752 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		AMFR_HUMAN (1-643): 0: 593: 100.00
+	Hs
		594657 PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42		AMFR_HUMAN (1-643): 0: 593: 100.00
+	Hs
		656658 PSB6_HUMAN (3-188): 2.95e-44: 148: 17.74		AMFR_HUMAN (1-643): 0: 593: 100.00
+	Hs
		656739 PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86		SYVN1_HUMAN (73-642): 5.72e-95: 306: 17.60
+	Hs
		1198660 PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80		SYVN1_HUMAN (73-642): 5.72e-95: 306: 17.60
+	Hs
		637713 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		SYVN1_HUMAN (73-642): 5.72e-95: 306: 17.60
+	Hs
		832129 PSB2_HUMAN (1-201): 5.46e-65: 200: 100.00		SYVN1_HUMAN (73-642): 5.72e-95: 306: 17.60
+	Hs
		594575 PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42		SYVN1_HUMAN (73-642): 5.72e-95: 306: 17.60
+	Hs
		656622 PSB6_HUMAN (3-188): 2.95e-44: 148: 17.74		SYVN1_HUMAN (73-642): 5.72e-95: 306: 17.60
+	Hs
		832117 PSB2_HUMAN (1-201): 5.46e-65: 200: 100.00		RNFT1_HUMAN (108-382): 5.3e-44: 165: 15.44
+	Mm
		610550 PSB8_MOUSE (2-196): 5.34e-67: 208: 19.49		CBL_MOUSE (293-550): 1.99e-37: 151: 18.73
+	Zm
		37345 A0A1D6Q5L0_MAIZE (2-186): 7.13e-62: 200: 19.79		A0A1D6M7Z6_MAIZE (326-640): 2.37e-33: 139: 13.76
+	Mm
		193606 PSB10_MOUSE (3-199): 3.53e-44: 149: 21.32		CBL_MOUSE (293-550): 1.99e-37: 151: 18.73