HitPredict

Interactor 1: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)
Gene: PSMB2

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	28514442, 33961781, 35271311, 17948026, 17189198
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 141
+	Hs
		656085 PSB8_HUMAN (2-196): 1.71e-68: 211: 19.49		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656796 PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		1152327 Q6IBT1_HUMAN (3-199): 1.38e-64: 202: 19.80		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		1303498 PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		638220 PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		637759 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		594663 PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		1367988 PSB2_DROME (1-195): 1.63e-81: 242: 44.10		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Hs
		771482 PSB10_HUMAN (3-199): 1.9e-45: 153: 21.83		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656662 PSB6_HUMAN (3-188): 2.95e-44: 148: 17.74		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		1178961 Q7K148_DROME (2-198): 6.07e-66: 205: 22.34		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367984 Q9VJJ0_DROME (1-195): 3.77e-66: 203: 51.28		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367996 Q9W470_DROME (2-199): 3.44e-64: 202: 19.70		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367991 Q9VUJ1_DROME (4-199): 3.12e-64: 201: 19.90		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		771316 PSA2_DROME (4-197): 4.6e-64: 199: 18.88		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50