HitPredict

Interactor 1: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)
Gene: PSMB2

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 33961781, 27503909, 35182481
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 522
+	Hs
		656798 PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		1303500 PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		638222 PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		637761 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		594668 PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656663 PSB6_HUMAN (3-188): 2.95e-44: 148: 17.74		FBX7_HUMAN (1-522): 0: 1102: 100.00